Researchers at the UCLA Health Jonsson Comprehensive Cancer Center have identified a new strategy to make cancer-fighting ...
New research in Cell Division shows that Bcl-2 overexpression promotes survival of cutaneous squamous cell carcinoma cells by ...
A new review argues that lipid nanoparticles, already clinically validated as mRNA carriers, could unify cancer therapy ...
The tumor suppressor protein p53 has been dubbed the "guardian of the genome" because it protects the DNA from stress or long-term damage by regulating the expression of numerous genes involved DNA ...
Researchers engineered hybrid strontium sulfite nanoparticle-modified lipid nanoparticles to deliver p53 mRNA, producing ...
Researchers at Massachusetts General Hospital (MGH) and Brigham and Women’s Hospital (BWH) have used mRNA nanoparticles to reprogram the tumor microenvironment of liver cancer and restore the function ...
Phase II study to evaluate surufatinib in patients with osteosarcoma and soft tissue sarcoma that has failed standard chemotherapy: Updated analysis. This is an ASCO Meeting Abstract from the 2024 ...
Can networks of genes be stimulated using resonance? Researchers at the Niels Bohr Institute are investigating whether the protein p53, which activates a range of different genes, can be induced to ...
A combination cancer therapy that relies on the reactivation of a tumor suppressor protein to kill leukemic and other blood ...
In a recent perspective published in the journal Cell Death and Differentiation, researchers in France, Germany, and Sweden discussed the unique mutational spectrum of the transformation-related ...