Researchers at the UCLA Health Jonsson Comprehensive Cancer Center have identified a new strategy to make cancer-fighting ...

New research in Cell Division shows that Bcl-2 overexpression promotes survival of cutaneous squamous cell carcinoma cells by ...

A combination cancer therapy that relies on the reactivation of a tumor suppressor protein to kill leukemic and other blood ...

The study, published in Frontiers in Immunology, found that temporarily activating a protein called p53 helped immune cells ...

The protein p53 is often called the guardian of the genome for its central role in preventing cancer. Yet paradoxically, it is also one of the most frequently mutated and dysfunctional proteins in ...

PMV Pharmaceuticals, Inc. (“PMV Pharma” or the “Company”; Nasdaq: PMVP), a precision oncology company pioneering the discovery and development of small molecule therapies targeting p53, today ...

Can networks of genes be stimulated using resonance? Researchers at the Niels Bohr Institute are investigating whether the protein p53, which activates a range of different genes, can be induced to ...

The tumor suppressor protein p53 has been dubbed the "guardian of the genome" because it protects the DNA from stress or long-term damage by regulating the expression of numerous genes involved DNA ...

Farber-led Immunity study shows that p53-mutant cancers can evade T-cell detection through several mechanisms, while ...

Cancer occurs when cells divide uncontrollably and displace healthy cells. Tumor suppressors provide an important defense against this. As molecular growth inhibitors, they prevent healthy cells from ...