The use of microarrays to analyse gene expression on a global level has recently received a great deal of attention. There has been much speculation about the power of this approach in the analysis of ...

The immune system is a 'cat's cradle' of networks operating at various levels, comprising a network of genetic and signaling pathways subtending a network of interacting cells. Hence, understanding ...

Abstract: In the diagnosis and treatment of cancer, cancer classification is a vital issue. Gene selection is much needed to solve the high dimensionality issue in microarray data, small sample size, ...

Abstract: In unsupervised learning literature, the study of clustering using microarray gene expression datasets has been extensively conducted with nonnegative matrix factorization (NMF), spectral ...

Scientists at ETH Zurich have identified a compound that sharply reduced nerve-cell death in mice engineered to develop ...

Correspondence to Professor Guangwen Cao, Department of Epidemiology, Second Military Medical University, 800 Xiangyin Rd., Shanghai 200433, China; gcao{at}smmu.edu.cn Objective Gene expression ...

Introduction Hepatocellular carcinoma (HCC) is a leading cause of cancer related death worldwide, with underlying liver cirrhosis (LC) the best recognised risk factor. Fibroblast growth factor 21 ...

Researchers at the University of California San Diego have developed a large-scale screening approach that identifies ...

A new genetic screening method allows researchers to efficiently modulate individual genes across entire tissues and provides ...

As genome editing therapies move through clinical trials to regulatory approval, scientists continue the quest for the holy ...

Colorectal cancer (CRC) remains one of the most heterogeneous malignancies, with substantial variability in molecular ...