From overcoming classical optical limits to tracking single proteins in real time, super-resolution imaging continues to ...

Abstract: Structured illumination microscopy (SIM) is an important super-resolution-based microscopy technique that breaks the diffraction limit and enhances optical microscopy systems. With the ...

Using artificial intelligence, engineers at the University of California San Diego have developed a new way to watch the inner workings of living cells in real time. The process both captures images ...

Schematic of the imaging process. Incoherent light, modulated by the DMD, is directed into the microscope and focused onto the sample plane by the objective lens, creating structured illumination for ...

Cells aren’t as passive as scientists once thought—they actively create internal currents to move proteins quickly and efficiently. These “cellular winds” push materials to the front of the cell, ...

Schematic of the imaging process. Incoherent light, modulated by the DMD, is directed into the microscope and focused onto the sample plane by the objective lens, creating structured illumination for ...

Researchers have shown that consumer-grade 3D printers and low-cost materials can be used to produce multi-element optical components that enable super-resolution imaging, with each lens costing less ...

3D SIM improves the lateral and axial resolution by a factor of 2 over conventional fluorescence microscopy and is compatible with multicolor imaging. The main limitations of 3D SIM are its low ...

Three-dimensional structured illumination microscopy (3D-SIM) doubles the resolution of fluorescence imaging in all directions and enables optical sectioning with increased image contrast. However, 3D ...

Abstract: Structured illumination microscopy (SIM) is a very important super-resolution microscopy technique, which provides high speed super-resolution with about two-fold spatial resolution ...

Abstract: The objective of optical super-resolution (SR) imaging is to acquire reliable sub-diffraction information on bioprocesses to facilitate scientific discovery. Structured illumination ...

Scientists at the Center for Cell Dynamics, School of Biological and Behavioral Sciences, Queen Mary University of London, in collaboration with Carl Zeiss, have developed an innovative live-cell ...